C-Statin Study – The major component of C-Statin is bindweed extract. Bindweed (Convolvulus Arvensis) is the most common weed in North America. Its extract (containing high molecular glycoproteins and polysaccharides) is a non-toxic anticancer agent. Cancer is surrounded by many small blood vessels (angiogenesis). If the angiogenesis is inhibited, cancer cells will be starved. Bindweed showed a strong angiogenesis inhibition effect on chick egg membrane model:
Without bindweed:
blood vessels grew toward the stimulating center.
With bindweed (200 µg):
no blood vessels responded to the stimulating center.
Immune system plays an important role in the anticancer battle. Bindweed boosted cellular immunity in cell culture.
Macrophage is a kind of white blood cell that can eat foreign invaders.
Lymphocyte is a kind of white blood cell that involves all kinds of immunity in the body.
Natural Killer (NK) cell is a kind of white blood cell that involves antitumor immunity.
Immune system plays an important role in the anticancer battle. Bindweed boosted cellular immunity in cell culture.
The bindweed extracts inhibited 53% of the melanoma (skin cancer) growth in mice.
The bindweed extracts inhibited 62% of the lung cancer growth in mice.
The bindweed extracts made the sarcoma mice live longer. All control mice were dead at 45 days but no bindweed mice died at 53 days.
The bindweed extracts were relatively non-toxic. The oral lethal dose (LD50) of BW was more than 20,000 mg/kg (100% alive in 7 days). It is in the range of “actual non-toxicity” like a food. The safe dose of bindweed extract can be 140 g a day for a 70 kg (156 lb) person.
