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CEA

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CEA is a tumor associated antigen. It is present in embryonic tissues and certain epithelial cancers. CEA was first thought to be specific for digestive tract cancers, however, it may also be elevated in other malignancies and in some nonmalignant diseases. CEA is elevated in those who smoke; infections and bowel diseases, liver disease and non-colorectal cancers. A persistent elevation in circulating CEA following treatment is strongly indication of metastatic or residual disease.Learn more about CEA »

Normal Values: Nonsmoker = 0.0 to 3.0 ng/mL, Smokers = 0.0 to 5.0 ng/mL

Processing Time: 10 calendar days

Processing Method: The methodology is by Microparticle Enzyme Immunoassay (MEIA) technology.

CPT Code: 82378

Patient Preparation: None

Special Instructions: Note whether patient is a smoker

Specimen Volume: 0.5 mL serum

Minimum Volume: 0.2 mL

Collection Container: SST or red-stopper tube

Transport Container: Plastic transport tube

Transport Instructions: Refrigerate or freeze

Causes for Rejection: Gross Hemolysis

References:
(1) Krupely, J., Gold, P., Freedman, S.O. Demonstration of Tumor-Specific Antigen of Human Digestive System. J Exp Med 1968;183:387.
(2) Hansen, H.J., et al. Solving the Problem of Antibody Interference in Commercial ""Sandwich""-Type Immunoassays of CEA. Clin. Chem. 1985;35:146.
(3) Martin, E.W., James, K.K., Hurtubise, P.E., et al.The Use of CEA as an Early Indicator for Gastrointestinal Tumor Recurrance and Second-Look Procedures, Cancer, 1977, 39(2):440-6.

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